Supporting world-class scientific and clinical research into sight loss

Ocular Surface Disease

The Roper-Hall Eye Foundation has purchased (through the Barbara Mary Wilmot Discretionary Trust) a Casia2 Ocular Coherence Tomography Scanner to assist in ground breaking research undertaken by Miss Saaeha Rauz, Clinical Reader in Translational Ophthalmology, University of Birmingham and Consultant Ophthalmologist, Birmingham and Midland Eye Centre.  

Optical coherence tomography (OCT), is a non-contact medical imaging technique that uses a laser as a light source to obtain a high-resolution cross-section of the human body and is one of the ground-breaking developments in ophthalmic science that enabled significant progress in the assessment of conditions affecting the retina (the innermost layer at the back of the eye), such as age-related macular degeneration. More recently advances in the field have enabled the application of this technology to the front of the eye. Using the Casia2 OCT scanner we hope to generate new imaging assessment techniques that will help researchers develop better treatments, and inform clinician decision making, thereby improving the care delivered to patients worldwide.


Our research projects include corneal infections, such as those acquired from contact lens wear, severe dry eye, ocular inflammation and chronic scarring conditions. Scarring of the eye may affect the cornea, which is the clear window of the eye, and the conjunctiva, which is the loose tissue that separates the eyeball from the external world, whilst keeping it moisturised and healthy. Damage to either of these tissues from scarring can be devastating and sight threatening. We are developing an anti-scarring eye drop for patients with corneal infections that will soon be tested in a clinical trial. Currently the techniques to assess corneal scarring are subject to considerable error and therefore there is a need for an unbiased test. As part of this project we aim to use the Casia2 to develop a software-based tool to assess the degree of scarring in the cornea of our patients.